Exercise interventions in children show negligible impact

Unfortunately there's just no way round reducing food intake.

http://www.medicalnewstoday.com/articles/250870.php

Although higher levels of physical activity are associated with lower body mass indices, exercise intervention programs are ineffective at lowering BMI.

The important thing about this review is that the studies did not rely on questionnaires. Questionnaire based studies are extremely prone to error, so this review only included studies using accelerometry devices.

Although previous studies have suggested such interventions don't achieve reductions in BMI because they make children eat more calories, this review found that total physical activity is not increased. In other words, adding extra exercise classes displaces other forms of activity or children naturally compensate by being less active at other times.

"Stop eating so much" is unfortunately the only solution to the problem.

Iron overload and diabetes

http://care.diabetesjournals.org/content/30/7/1926.full

A few links concerning alcohol dehydrogenase

In the American Journal of Clinical Nutrition:

Alterations of Alcohol Dehydrogenase and Other Hepatic Enzymes Following Oral Alcohol Intoxication

In the Journal of the National Cancer Institute:

Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers.

Comment on above article here


In Life Sciences:

The effects of pregnancy on ethanol clearance.

From Livestrong.com
Alcohol Dehydrogenase and Breast Cancer


The effect that Ranitidine might have on gastric alcohol dehydrogenase

In Oxford Journals

GASTRIC ALCOHOL DEHYDROGENASE ACTIVITY IN MAN...

An interesting summary of how alcohol is broken down

a

Can exercise really boost metabolism?

Most people believe that it can and the answer appears to be "yes, but only a little bit".

According to Dr Len Kravitz from the University of New Mexico, resistance exercise can increase muscle mass by about 2kg in the average person thus allowing an extra energy burn of 50kcal/day. Aerobic exercise does NOT increase resting metabolic rate.

Read the whole story here: http://www.fitcommerce.com/Blueprint/Page.aspx?pageId=577&tabindex=5

Dr Kravitz introduces the concept of NEAT: Non exercise activity thermogenesis - i.e. all non-structured physical activity. He seems to be stating that NEAT can be increased by for example by "parking at the furthest place in the car park". This may be included in the definition of NEAT, but what I am more interested in is subconscious physical activity such as fidgeting.

Your body fat is an organ - adipokine secretions

 PMID 20681635 Identification of novel human adipocyte secreted proteins by using SGBS cells

Cholesterol does not predict stroke in women and is a very poor indicator in men

Annals of Neurology - Nonfasting triglycerides, cholesterol, and ischemic stroke in the general population


BBC News: Cholesterol 'does not predict stroke in women'


Cholesterol has long been blamed for causing strokes in spite of the heroic efforts of groups like The International Association of Cholesterol Sceptics. This study shows that cholesterol is irrelevant in women and not especially relevant in men.

Pandemrix and Narcolepsy linked

The World Health Organisation has called for a closer look at a potential link between GlaxoSmithKline's pandemic swine flu vaccine Pandemrix and the development of the chronic sleep disorder narcolepsy.

The group's Global Advisory Committee on Vaccine Safety said in a statement that "further investigation is warranted" after a 12 different countries reported cases of the condition in children and adolescents following vaccination with GSK's product.



Read the full article here: