PMID 14594788
Antioxidant vitamins and mortality in older persons: findings from the nutrition add-on study to the Medical Research Council Trial of Assessment and Management of Older People in the Community. (American Journal of Clinical Nutrition in 2003)
Conclusion: Low blood vitamin C concentrations in the older British population are strongly predictive of mortality.
Therefore I suggest that you are insane if you are old and do not take a large dose of vitamin C daily, since it is a totally harmless compound when taken in divided doses throughout the day.
HOWEVER, the fact that a low blood concentration of X predicts mortality does not necessarily mean that artificially adjusting the concentration will reduce mortality. Retaining all hair into your fifties rather than going bald when you are young is predictive of prostate cancer but getting laser hair removal on your scalp is not going to help. In the same way, low blood concentrations of vitamin C may simply be indicative of another more serious problem.
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